You are informing someone that there is something not right or out of the ordinary.

Here are some examples:

There is something wrong with my laptop.
There is something wrong with my car.
There is something wrong with my cell phone.
There is something wrong with my head.
There is something wrong with your answering machine.
There is something wrong with your way of thinking.
There is something wrong with your attitude.
There is something wrong with your dog.
There is something wrong with our relationship.
There is something wrong with our alarm clock.

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